Asymmetric Mean First Passage Time for DNA Translocation Through a Nanopore
نویسنده
چکیده
We studied the Mean first passage time for the DNA translocation through a narrow pore. We also proved that, for an asymmetric rachet potential, the mean first passage time for the same DNA to translocate through the membrane can be different when passing from the two different ends, even without external potential. We further extended the situation to a more general case, where a periodic chain with N subunits and m steps in each subunit is studied, and we proved that the difference of the two mean first passage time is of the order linear to the number to periodicity. We also explained the reason for the more distinct difference between MFPT when external potential is present.
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